Plasticity without phenomenology: A first step

τέχνη: A First Step

A new approach to the design of the computing curriculum for a Bachelor of Arts degree is described. The approach relies extensively on problem-based instruction and computer graphics. The novelty arises from the magnitude and origin of the problems to be integrated into the curriculum and the breadth of the impact across the curriculum. Results from a trial course, the first experiment with th...

Synaptic plasticity: one STEP at a time.

Striatal enriched tyrosine phosphatase (STEP) has recently been identified as a crucial player in the regulation of synaptic function. It is restricted to neurons within the CNS and acts by downregulating the activity of MAP kinases, the tyrosine kinase Fyn and NMDA receptors. By modulating these substrates, STEP acts on several parallel pathways that impact upon the progression of synaptic pla...

Mapping Model: A First Step to Ensure Usability for sustaining User Interface Plasticity

Ubiquitous computing has amplified the need for interactive systems to be able to adapt to their context of use () while preserving usability. This property is called plasticity. Until now, efforts have been put on the functional aspect of adaptation, neglecting the usability part of the definition. This paper investigates MDE mappings for embedding both the descrip...

Disclosure: only a first step.

Synaptic plasticity: Step-wise strengthening

Recent studies suggest that the strength of synapses in the brain may change in a step-wise manner, rather than continuously.